Metabolic reprogramming and immune evasion: the interplay in the tumor microenvironment

• Hlavní autoři: Haixia Zhang (Autor), Shizhen Li (Autor), Dan Wang (Autor), Siyang Liu (Autor), Tengfei Xiao (Autor), Wangning Gu (Autor), Hongmin Yang (Autor), Hui Wang (Autor), Minghua Yang (Autor), Pan Chen (Autor)
• Médium: Kniha
• Vydáno: BMC, 2024-09-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Tumor cells possess complex immune evasion mechanisms to evade immune system attacks, primarily through metabolic reprogramming, which significantly alters the tumor microenvironment (TME) to modulate immune cell functions. When a tumor is sufficiently immunogenic, it can activate cytotoxic...