Local intraluminal delivery of a smooth muscle-targeted RNA ligand inhibits neointima growth in a porcine model of peripheral vascular disease

• Main Authors: Saami K. Yazdani (Author), Beilei Lei (Author), Claire V. Cawthon (Author), Kathryn Cooper (Author), Clifton Huett (Author), Paloma H. Giangrande (Author), Francis J. Miller, Jr (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Anti-proliferative agents have been the primary therapeutic drug of choice to inhibit restenosis after endovascular treatment. However, recent safety and efficacy concerns for patients who underwent peripheral artery disease revascularization have demonstrated the need for alternative therapeutics....