Synthesis and Characterization of a New Norfloxacin/Resorcinol Cocrystal with Enhanced Solubility and Dissolution Profile

A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate forms with the same (1:1) Norfloxacin/resorcinol st...

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Main Authors: Hanan Fael (Author), Rafael Barbas (Author), Rafel Prohens (Author), Clara Ràfols (Author), Elisabet Fuguet (Author)
Format: Book
Published: MDPI AG, 2021-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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