Synthesis and Characterization of a New Norfloxacin/Resorcinol Cocrystal with Enhanced Solubility and Dissolution Profile

• मुख्य लेखकों: Hanan Fael (लेखक), Rafael Barbas (लेखक), Rafel Prohens (लेखक), Clara Ràfols (लेखक), Elisabet Fuguet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate forms with the same (1:1) Norfloxacin/resorcinol st...