TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy

• Main Authors: Zakaria Grada (Author), Meenakshi Hegde (Author), Tiara Byrd (Author), Donald R Shaffer (Author), Alexia Ghazi (Author), Vita S Brawley (Author), Amanda Corder (Author), Kurt Schönfeld (Author), Joachim Koch (Author), Gianpietro Dotti (Author), Helen E Heslop (Author), Stephen Gottschalk (Author), Winfried S Wels (Author), Matthew L Baker (Author), Nabil Ahmed (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeted T cells are emerging as effective non-toxic therapies for cancer. Multiple elements, however, contribute to the overall pathogenesis of cancer through both distinct and redundant mechanisms. Hence, targeting multiple cancer-specific markers simultaneously could result in better therapeutic...