Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

• Main Authors: Zheng Jin (Author), Wenbo Zhang (Author), Yuan Luo (Author), Xiushen Li (Author), Lijin Qing (Author), Qiang Zuo (Author), Junfeng Fang (Author), Wei Wu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Qingre Huoxue (QRHX) decoction, a traditional Chinese medicine, has been widely used to prevent and treat myocardial infarction (MI). Objective This study elucidates the possible mechanisms of QRHX in preventing or treating MI in a rat model. Materials and methods The chemical constituents o...