Preclinical In Vitro Investigation of MDM2 Inhibition in Combination with Antiangiogenic Therapy for Breast Cancer Treatment

• Main Authors: Ali M. Alaseem (Author), Khalid Alhazzani (Author), Ahmed Zuwaiel Alanazi (Author), Yasser Alqarni (Author), Mohammad M. Algahtani (Author), Abdullah S. Alhamed (Author), Glowi Alasiri (Author), Fahad T. Alotaibi (Author), Talha Jawaid (Author), Jehad A. Aldali (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Combining antiangiogenic drugs with other chemotherapeutic drugs has been found to produce superior therapeutic outcomes and prevent drug resistance in a variety of cancers. Methods: Experimental assays such as the MTT assay, flow cytometry, western blotting, and qPCR have been used to e...