Nonlinear relationship between enteric-coated mycophenolate sodium dose and mycophenolic acid exposure in Han kidney transplantation recipients

• Main Authors: Jun Zhang (Author), Mengmeng Jia (Author), Lihua Zuo (Author), Na Li (Author), Yonggang Luo (Author), Zhi Sun (Author), Xiaojian Zhang (Author), Zhenfeng Zhu (Author)
• Format: Book
• Published: Elsevier, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the research was to investigate the pharmacokinetics (PK) of enteric-coated mycophenolate sodium (EC-MPS) by quantification of the active metabolite of mycophenolic acid (MPA) after multiple escalating oral doses in Han kidney transplant recipients. A total of 28 Han postoperative kidney...