Pulmonary transcriptome analysis in the surgically induced rabbit model of diaphragmatic hernia treated with fetal tracheal occlusion

• Main Authors: Alexander C. Engels (Author), Paul D. Brady (Author), Molka Kammoun (Author), Julio Finalet Ferreiro (Author), Philip DeKoninck (Author), Masayuki Endo (Author), Jaan Toelen (Author), Joris R. Vermeesch (Author), Jan Deprest (Author)
• Format: Book
• Published: The Company of Biologists, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital diaphragmatic hernia (CDH) is a malformation leading to pulmonary hypoplasia, which can be treated in utero by fetal tracheal occlusion (TO). However, the changes of gene expression induced by TO remain largely unknown but could be used to further improve the clinically used prenatal trea...