Late morfofunctional alterations of the Sertoli cell caused by doxorubicin administered to prepubertal rats

• Main Authors: Brilhante Otávio (Author), Okada Fatima K (Author), Sasso-Cerri Estela (Author), Stumpp Taiza (Author), Miraglia Sandra M (Author)
• Format: Book
• Published: BMC, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Doxorubicin is a potent chemotherapeutic drug used against a variety of cancers. It acts through interaction with polymerases and topoisomerase II and free radical production. Doxorubicin activity is not specific to cancer cells and...