XenoCell: classification of cellular barcodes in single cell experiments from xenograft samples

• Autores principales: Stefano Cheloni (Autor), Roman Hillje (Autor), Lucilla Luzi (Autor), Pier Giuseppe Pelicci (Autor), Elena Gatti (Autor)
• Formato: Libro
• Publicado: BMC, 2021-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Single-cell sequencing technologies provide unprecedented opportunities to deconvolve the genomic, transcriptomic or epigenomic heterogeneity of complex biological systems. Its application in samples from xenografts of patient-derived biopsies (PDX), however, is limited by the pr...