The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy

• Main Authors: Tao-Ran Li (Author), Yan-Jie Jia (Author), Chao Ma (Author), Wen-Ying Qiu (Author), Qun Wang (Author), Xiao-Qiu Shao (Author), Rui-Juan Lv (Author)
• Format: Book
• Published: The Company of Biologists, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence indicates that neuroinflammation plays a crucial role in the pathogenesis of temporal lobe epilepsy (TLE). However, it is unclear how the perpetuate inflammation develops. Some recent studies have suggested the possible involvement of microRNA-146a (miR-146a) in the modulation of...