METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway

• Main Authors: Hui Han (Author), Chunlong Yang (Author), Shuishen Zhang (Author), Maosheng Cheng (Author), Siyao Guo (Author), Yan Zhu (Author), Jieyi Ma (Author), Yu Liang (Author), Lu Wang (Author), Siyi Zheng (Author), Zhaoyu Wang (Author), Demeng Chen (Author), Yi-Zhou Jiang (Author), Shuibin Lin (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Esophageal cancer is a lethal malignancy with a high mortality rate, while the molecular mechanisms underlying esophageal cancer pathogenesis are still poorly understood. Here, we found that the N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3) is significantly upregulated in esophageal squ...