METTL3-mediated m6A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway

• Главные авторы: Hui Han (Автор), Chunlong Yang (Автор), Shuishen Zhang (Автор), Maosheng Cheng (Автор), Siyao Guo (Автор), Yan Zhu (Автор), Jieyi Ma (Автор), Yu Liang (Автор), Lu Wang (Автор), Siyi Zheng (Автор), Zhaoyu Wang (Автор), Demeng Chen (Автор), Yi-Zhou Jiang (Автор), Shuibin Lin (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2021-12-01T00:00:00Z.
• Предметы: article
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Esophageal cancer is a lethal malignancy with a high mortality rate, while the molecular mechanisms underlying esophageal cancer pathogenesis are still poorly understood. Here, we found that the N6-methyladenosine (m6A) methyltransferase-like 3 (METTL3) is significantly upregulated in esophageal squ...