Development of DNA aptamers for visualization of glial brain tumors and detection of circulating tumor cells

• Main Authors: Anna S. Kichkailo (Author), Andrey A. Narodov (Author), Maria A. Komarova (Author), Tatiana N. Zamay (Author), Galina S. Zamay (Author), Olga S. Kolovskaya (Author), Evgeniy E. Erakhtin (Author), Yury E. Glazyrin (Author), Dmitry V. Veprintsev (Author), Roman V. Moryachkov (Author), Vladimir V. Zabluda (Author), Irina Shchugoreva (Author), Polina Artyushenko (Author), Vladimir A. Mironov (Author), Dmitry I. Morozov (Author), Vladimir A. Khorzhevskii (Author), Anton V. Gorbushin (Author), Anastasia A. Koshmanova (Author), Elena D. Nikolaeva (Author), Igor P. Grinev (Author), Ivan I. Voronkovskii (Author), Daniil S. Grek (Author), Kirill V. Belugin (Author), Alexander A. Volzhentsev (Author), Oleg N. Badmaev (Author), Natalia A. Luzan (Author), Kirill A. Lukyanenko (Author), Georgy Peters (Author), Ivan N. Lapin (Author), Andrey K. Kirichenko (Author), Petr V. Konarev (Author), Evgeny V. Morozov (Author), Gleb G. Mironov (Author), Ana Gargaun (Author), Darija Muharemagic (Author), Sergey S. Zamay (Author), Elena V. Kochkina (Author), Maya A. Dymova (Author), Tatiana E. Smolyarova (Author), Alexey E. Sokolov (Author), Andrey A. Modestov (Author), Nikolay A. Tokarev (Author), Nikolay V. Shepelevich (Author), Anastasia V. Ozerskaya (Author), Natalia G. Chanchikova (Author), Alexey V. Krat (Author), Ruslan A. Zukov (Author), Varvara I. Bakhtina (Author), Pavel G. Shnyakin (Author), Pavel A. Shesternya (Author), Valery A. Svetlichnyi (Author), Marina M. Petrova (Author), Ivan P. Artyukhov (Author), Felix N. Tomilin (Author), Maxim V. Berezovski (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex vivo, and in vivo for visualization diagnostics of central nervous system tumors. We selected the aptamers binding specifically to the postoperative human glial primary tumors and not to the healthy brain cel...