Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish

• Egile Nagusiak: Karin Tuschl (Egilea), Richard J. White (Egilea), Chintan Trivedi (Egilea), Leonardo E. Valdivia (Egilea), Stephanie Niklaus (Egilea), Isaac H. Bianco (Egilea), Chris Dadswell (Egilea), Ramón González-Méndez (Egilea), Ian M. Sealy (Egilea), Stephan C. F. Neuhauss (Egilea), Corinne Houart (Egilea), Jason Rihel (Egilea), Stephen W. Wilson (Egilea), Elisabeth M. Busch-Nentwich (Egilea)
• Formatua: Liburua
• Argitaratua: The Company of Biologists, 2022-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Manganese neurotoxicity is a hallmark of hypermanganesemia with dystonia 2, an inherited manganese transporter defect caused by mutations in SLC39A14. To identify novel potential targets of manganese neurotoxicity, we performed transcriptome analysis of slc39a14−/− mutant zebrafish that were exposed...