Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy

• Main Authors: Yifei Chen (Author), Fangpu Yu (Author), Yu Zhang (Author), Mengmeng Li (Author), Mingxue Di (Author), Weijia Chen (Author), Xiaolin Liu (Author), Yun Zhang (Author), Mei Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tongxinluo (TXL), a traditional Chinese medication, plays a key role in the formation and progression of plaques in atherosclerosis. The formation of foam cells by macrophages accelerates the destabilisation of plaques. In previous research, we had found that TXL significantly inhibits ox-LDL-induce...