Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity

Cyclophilin J (CyPJ), also called peptidylprolyl isomerase like 3, has been identified as a novel member of the cyclophilin family. Our previous research has resolved the three-dimensional structure of CyPJ and demonstrated the peptidylprolyl cis-trans isomerase (PPIase) activity of CyPJ, which can...

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Main Authors: Xuemei Zhao (Author), Chengcai Xia (Author), Xiaodan Wang (Author), Hao Wang (Author), Ming Xin (Author), Long Yu (Author), Yulong Liang (Author)
Format: Book
Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
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