Development of a Carvedilol Oral Liquid Formulation for Paediatric Use

• Main Authors: Blanca Chiclana-Rodríguez (Author), Encarnacion Garcia-Montoya (Author), Khadija Rouaz-El Hajoui (Author), Miquel Romero-Obon (Author), Anna Nardi-Ricart (Author), Marc Suñé-Pou (Author), Josep M. Suñé-Negre (Author), Pilar Pérez-Lozano (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Carvedilol (CARV) is an 'off-label' β-blocker drug to treat cardiovascular diseases in children. Since CARV is nearly insoluble in water, only CARV solid forms are commercialized. Usually, CARV tablets are manipulated to prepare an extemporaneous liquid formulation for children in hospital...