Plasma infliximab monitoring contributes to optimize Takayasu arteritis treatment: a case report

• Main Authors: Sho Masui (Author), Atsushi Yonezawa (Author), Kazushi Izawa (Author), Makoto Hayakari (Author), Kayoko Asakura (Author), Risa Taniguchi (Author), Masahiko Isa (Author), Hirofumi Shibata (Author), Takahiro Yasumi (Author), Ryuta Nishikomori (Author), Junko Takita (Author), Kazuo Matsubara (Author)
• Format: Book
• Published: BMC, 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Infliximab (IFX), a mouse-human chimeric monoclonal antibody against human tumor necrosis factor alpha, is used in refractory cases of Takayasu arteritis. Several factors influence the pharmacokinetics of therapeutic antibodies including IFX. Monitoring plasma levels of IFX could...