Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway

• Główni autorzy: Chenjing Xu (Autor), Ziping Ye (Autor), Wenyu Jiang (Autor), Shu Wang (Autor), Hongjie Zhang (Autor)
• Format: Książka
• Wydane: BMC, 2023-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background The aberrant formation of neutrophil extracellular traps (NETs) has been implicated in ulcerative colitis (UC), a chronic recurrent intestinal inflammation. Cyclosporine A (CsA) is now applied as rescue therapy for acute severe UC. In addition, it has been certained that CsA inhi...