Cyclosporine A alleviates colitis by inhibiting the formation of neutrophil extracellular traps via the regulating pentose phosphate pathway

Abstract Background The aberrant formation of neutrophil extracellular traps (NETs) has been implicated in ulcerative colitis (UC), a chronic recurrent intestinal inflammation. Cyclosporine A (CsA) is now applied as rescue therapy for acute severe UC. In addition, it has been certained that CsA inhi...

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Main Authors: Chenjing Xu (Author), Ziping Ye (Author), Wenyu Jiang (Author), Shu Wang (Author), Hongjie Zhang (Author)
Format: Book
Published: BMC, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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