Recombinant Peptide Production Platform Coupled with Site-Specific Albumin Conjugation Enables a Convenient Production of Long-Acting Therapeutic Peptide

• Main Authors: Mijeong Bak (Author), Junyong Park (Author), Kiyoon Min (Author), Jinhwan Cho (Author), Jihyoun Seong (Author), Young S. Hahn (Author), Giyoong Tae (Author), Inchan Kwon (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The number of therapeutic peptides for human treatment is growing rapidly. However, their development faces two major issues: the poor yield of large peptides from conventional solid-phase synthesis, and the intrinsically short serum half-life of peptides. To address these issues, we investigated a...