The chromatin remodeling BAP complex limits tumor-promoting activity of the Hippo pathway effector Yki to prevent neoplastic transformation in Drosophila epithelia

Switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complexes are mutated in many human cancers. In this article, we make use of a Drosophila genetic model for epithelial tumor formation to explore the tumor suppressive role of SWI/SNF complex proteins. Members of the BAP complex exhibit t...

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Main Authors: Shilin Song (Author), Héctor Herranz (Author), Stephen M. Cohen (Author)
Format: Book
Published: The Company of Biologists, 2017-10-01T00:00:00Z.
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3rd Floor Main Library

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