Steering Away from Current Amoxicillin Dose Reductions in Hospitalized Patients with Impaired Kidney Function to Avoid Subtherapeutic Drug Exposure

• Main Authors: Cornelis Smit (Author), Swapnoleena Sen (Author), Elodie von Dach (Author), Abderrahim Karmime (Author), Pierre Lescuyer (Author), David Tonoli (Author), Julia Bielicki (Author), Angela Huttner (Author), Marc Pfister (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current dose reductions recommended for amoxicillin in patients with impaired kidney function could lead to suboptimal treatments. In a prospective, observational study in hospitalized adults with varying kidney function treated with an IV or oral dose of amoxicillin, amoxicillin concentrations were...