Pharmacokinetic, Pharmacokinetic/Pharmacodynamic, and Safety Investigations of Lefamulin in Healthy Chinese Subjects

• Main Authors: Yingying Hu (Author), Qiong Wei (Author), Xingchen Bian (Author), Xinyi Yang (Author), Jicheng Yu (Author), Jingjing Wang (Author), Haijing Yang (Author), Guoying Cao (Author), Xiaojie Wu (Author), Jing Zhang (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to explore the pharmacokinetics (PK) and safety of oral (PO) and intravenous (IV) lefamulin in healthy Chinese subjects and to evaluate the efficacy of the intravenous administration regimen using pharmacokinetic/pharmacodynamic (PK/PD) analysis. This study was a randomized, open-la...