Cysteinyl leukotrienes pathway genes, atopic asthma and drug response: From population isolates to large genome-wide association studies.

• 主要な著者: Miles Douglas Thompson (著者), Valeri Capra (著者), Mark Clunes (著者), G. Enrico Rovati (著者), Mary Maj (著者), Jana Stankova (著者), David Duffy (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Genetic studies have identified genetic variants associated with asthma pathogenesis and altered response to drug therapy. Many studies implicate polymorphisms in genes encoding the enzymes responsible for leukotriene synthesis and intracellular signaling through activation of seven transmembrane do...