Cysteinyl leukotrienes pathway genes, atopic asthma and drug response: From population isolates to large genome-wide association studies.

• Main Authors: Miles Douglas Thompson (Author), Valeri Capra (Author), Mark Clunes (Author), G. Enrico Rovati (Author), Mary Maj (Author), Jana Stankova (Author), David Duffy (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genetic studies have identified genetic variants associated with asthma pathogenesis and altered response to drug therapy. Many studies implicate polymorphisms in genes encoding the enzymes responsible for leukotriene synthesis and intracellular signaling through activation of seven transmembrane do...