Comparison of Paliperidone Palmitate from Different Crystallization Processes and Effect on Formulations In Vitro and In Vivo

• Main Authors: Junfeng Shi (Author), Dan Wang (Author), Yang Tian (Author), Zengming Wang (Author), Jing Gao (Author), Nan Liu (Author), Xiang Gao (Author), Aiping Zheng (Author), Hui Zhang (Author), Meixian Xiang (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The quality of active pharmaceutical ingredients (APIs) is an important factor which can affect the safety and efficacy of pharmaceuticals. This study was designed to investigate the nature of paliperidone palmitate (PP) obtained by different crystallization processes, then compare the characteristi...