Determination of SFRP1 and SFRP2 Genes Promoter Methylation Status in Patients with Chronic Myelogenous Leukemia

• Main Authors: Elahe Derakhshanfar (Author), Shaban Alizadeh (Author), Hassan Rafiemehr (Author), Fateme Nadali (Author), Ali Qasemi (Author), Masuod Karimi (Author), Nushin Shabab (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Aim: Chronic myeloid leukemia (CML) is a myeloprolifrative neoplasm that is characterized by an expansion of myeloid, erythroid cells and platelets in peripheral blood and myeloid hyperplasia in bone marrow. Secreted frizzled-related protein family is a negative regulator of the Wnt s...