Association Between KCNJ6 (GIRK2) Gene Polymorphism rs2835859 and Post-operative Analgesia, Pain Sensitivity, and Nicotine Dependence

• Autores principales: Daisuke Nishizawa (Autor), Ken-ichi Fukuda (Autor), Shinya Kasai (Autor), Yasukazu Ogai (Autor), Junko Hasegawa (Autor), Naomi Sato (Autor), Hidetaka Yamada (Autor), Fumihiko Tanioka (Autor), Haruhiko Sugimura (Autor), Masakazu Hayashida (Autor), Kazutaka Ikeda (Autor)
• Formato: Libro
• Publicado: Elsevier, 2014-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract.: G-protein-activated inwardly rectifying potassium (GIRK) channels are expressed in many tissues and activated by several Gi/o protein-coupled receptors, such as opioid and dopamine receptors, and thus are known to be involved in the modulation of opioid-induced analgesia, pain, and reward...