Association Between KCNJ6 (GIRK2) Gene Polymorphism rs2835859 and Post-operative Analgesia, Pain Sensitivity, and Nicotine Dependence

• Main Authors: Daisuke Nishizawa (Author), Ken-ichi Fukuda (Author), Shinya Kasai (Author), Yasukazu Ogai (Author), Junko Hasegawa (Author), Naomi Sato (Author), Hidetaka Yamada (Author), Fumihiko Tanioka (Author), Haruhiko Sugimura (Author), Masakazu Hayashida (Author), Kazutaka Ikeda (Author)
• Format: Book
• Published: Elsevier, 2014-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: G-protein-activated inwardly rectifying potassium (GIRK) channels are expressed in many tissues and activated by several Gi/o protein-coupled receptors, such as opioid and dopamine receptors, and thus are known to be involved in the modulation of opioid-induced analgesia, pain, and reward...