Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest

• Main Authors: Deepika Sankaran (Author), Payam Vali (Author), Praveen Chandrasekharan (Author), Peggy Chen (Author), Sylvia F. Gugino (Author), Carmon Koenigsknecht (Author), Justin Helman (Author), Jayasree Nair (Author), Bobby Mathew (Author), Munmun Rawat (Author), Lori Nielsen (Author), Amy L. Lesneski (Author), Morgan E. Hardie (Author), Ziad Alhassen (Author), Houssam M. Joudi (Author), Evan M. Giusto (Author), Lida Zeinali (Author), Heather K. Knych (Author), Gary M. Weiner (Author), Satyan Lakshminrusimha (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The 7th edition of the <i>Textbook of Neonatal Resuscitation</i> recommends administration of epinephrine via an umbilical venous catheter (UVC) inserted 2-4 cm below the skin, followed by a 0.5-mL to 1-mL flush for severe bradycardia despite effective ventilation and chest compressions...