Biologically stable threose nucleic acid-based probes for real-time microRNA detection and imaging in living cells
We successfully fabricated threose nucleic acid (TNA)-based probes for real-time monitoring of target miRNA levels in cells. Our TNA probe is comprised of a fluorophore-labeled TNA reporter strand by partially hybridizing to a quencher-labeled TNA that is designed to be antisense to a target RNA tra...
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Main Authors: | Fei Wang (Author), Ling Sum Liu (Author), Pan Li (Author), Hoi Man Leung (Author), Dick Yan Tam (Author), Pik Kwan Lo (Author) |
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Format: | Book |
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Elsevier,
2022-03-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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