Enhanced Antibacterial Efficacy of Bioceramic Implants Functionalized with Ciprofloxacin: An In Silico and In Vitro Study

• Main Authors: Renata-Maria Văruț (Author), Luciana Teodora Rotaru (Author), Diana Cimpoesu (Author), Mihaela Corlade (Author), Cristina Elena Singer (Author), Alin Iulian Silviu Popescu (Author), Cristina Popescu (Author), Iliescu Iulian-Nicolae (Author), Adriana Mocanu (Author), Mihaela Popescu (Author), Mihai Alexandru Butoi (Author), Oana Elena Nicolaescu (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study explores the antibacterial efficacy and cytotoxicity of ciprofloxacin-functionalized bioceramic implants. We synthesized hydroxyapatite-ciprofloxacin (HACPX_CS) composites and applied them to titanium substrates (Ti-HA-CPX), evaluating their performance in vitro agai...