Synergic action of L-acetylcarnitine and L-methylfolate in Mouse Models of Stress-Related Disorders and Human iPSC-Derived Dopaminergic Neurons

• المؤلفون الرئيسيون: Rosamaria Orlando (مؤلف), Roxana Paula Ginerete (مؤلف), Laura Cavalleri (مؤلف), Vincenza Aliperti (مؤلف), Tiziana Imbriglio (مؤلف), Giuseppe Battaglia (مؤلف), Anna Rita Zuena (مؤلف), Ferdinando Nicoletti (مؤلف), Emilio Merlo Pich (مؤلف), Ginetta Collo (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The epigenetic agents, L-acetylcarnitine (LAC) and L-methylfolate (MF) are putative candidates as add-on drugs in depression. We evaluated the effect of a combined treatment with LAC and MF in two different paradigms of chronic stress in mice and in human inducible pluripotent stem cells (hiPSCs) di...