Induction of Heme Oxygenase-1 by 15d-Prostaglandin J<sub>2</sub> Mediated via a ROS-Dependent Sp1 and AP-1 Cascade Suppresses Lipopolysaccharide-Triggered Interleukin-6 Expression in Mouse Brain Microvascular Endothelial Cells

Heme oxygenase-1 (HO-1) has been shown to exert antioxidant, anti-inflammatory, and anti-apoptotic effects in various types of cells. Therefore, the induction of HO-1 is an excellent rationale for the development of protective drugs. 15-Deoxy-Δ<sup>12,14</sup>-prostaglandin J<sub>2...

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Hoofdauteurs: Chien-Chung Yang (Auteur), Li-Der Hsiao (Auteur), Ya-Fang Shih (Auteur), Ching-I Chang (Auteur), Chuen-Mao Yang (Auteur)
Formaat: Boek
Gepubliceerd in: MDPI AG, 2022-04-01T00:00:00Z.
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