Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers

• Main Authors: Junjun Li (Author), Itsunari Minami (Author), Leqian Yu (Author), Kiyotaka Tsuji (Author), Minako Nakajima (Author), Jing Qiao (Author), Masato Suzuki (Author), Ken Shimono (Author), Norio Nakatsuji (Author), Hitetoshi Kotera (Author), Li Liu (Author), Yong Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes (CMs) hold high potential for use in drug assessment and myocardial regeneration. To create tissue-like constructs of CMs for extracellular monitoring, we placed aligned fibers (AFs) on the surface of a microelectrode array and then...