Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency.

• المؤلفون الرئيسيون: Natnaree Saiprom (مؤلف), Tanes Sangsri (مؤلف), Sarunporn Tandhavanant (مؤلف), Sineenart Sengyee (مؤلف), Rungnapa Phunpang (مؤلف), Anucha Preechanukul (مؤلف), Uriwan Surin (مؤلف), Apichai Tuanyok (مؤلف), Ganjana Lertmemongkolchai (مؤلف), Wasun Chantratita (مؤلف), T Eoin West (مؤلف), Narisara Chantratita (مؤلف)
• التنسيق: كتاب
• منشور في: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

<h4>Background</h4>Burkholderia pseudomallei is an environmental bacterium that causes melioidosis. A facultative intracellular pathogen, B. pseudomallei can induce multinucleated giant cells (MNGCs) leading to plaque formation in vitro. B. pseudomallei can switch colony morphotypes unde...