Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency.

• Glavni autori: Natnaree Saiprom (Autor), Tanes Sangsri (Autor), Sarunporn Tandhavanant (Autor), Sineenart Sengyee (Autor), Rungnapa Phunpang (Autor), Anucha Preechanukul (Autor), Uriwan Surin (Autor), Apichai Tuanyok (Autor), Ganjana Lertmemongkolchai (Autor), Wasun Chantratita (Autor), T Eoin West (Autor), Narisara Chantratita (Autor)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2020-09-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<h4>Background</h4>Burkholderia pseudomallei is an environmental bacterium that causes melioidosis. A facultative intracellular pathogen, B. pseudomallei can induce multinucleated giant cells (MNGCs) leading to plaque formation in vitro. B. pseudomallei can switch colony morphotypes unde...