Pharmacological OGG1 inhibition decreases murine allergic airway inflammation

• Main Authors: Lloyd Tanner (Author), Jesper Bergwik (Author), Ravi K. V. Bhongir (Author), Lang Pan (Author), Caijuan Dong (Author), Olov Wallner (Author), Christina Kalderén (Author), Thomas Helleday (Author), Istvan Boldogh (Author), Mikael Adner (Author), Arne Egesten (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aim: Allergic asthma is a complex inflammatory disease involving type 2 innate lymphoid cells, type 2 T helper cells, macrophages, and eosinophils. The disease is characterized by wheezing, dyspnea, coughing, chest tightness and variable airflow limitation for which there is no cure a...