The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats
Extracellular matrix (ECM) remodelling of the adipose tissue plays a pivotal role in the pathophysiology of obesity. The lysyl oxidase (LOX) family of amine oxidases, including LOX and LOX-like (LOXL) isoenzymes, controls ECM maturation, and upregulation of LOX activity is essential in fibrosis; how...
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Main Authors: | María Miana (Author), María Galán (Author), Ernesto Martínez-Martínez (Author), Saray Varona (Author), Raquel Jurado-López (Author), Belén Bausa-Miranda (Author), Alfonso Antequera (Author), María Luaces (Author), José Martínez-González (Author), Cristina Rodríguez (Author), Victoria Cachofeiro (Author) |
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Format: | Book |
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The Company of Biologists,
2015-06-01T00:00:00Z.
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