TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis

• Main Authors: Emmanuelle Rochette (Author), Pierre Bourdier (Author), Bruno Pereira (Author), Eric Doré (Author), Anthony Birat (Author), Sébastien Ratel (Author), Stéphane Echaubard (Author), Pascale Duché (Author), Etienne Merlin (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Children with juvenile idiopathic arthritis (JIA) have impaired physical abilities. TNF-α plays a crucial role in this pathogenesis, but it is also involved in the use of lipids and muscle health. Objective of this study was to explore substrate oxidation and impact of TNF blocka...