The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial

The Effects of Melatonin on the Descending Pain Inhibitory System and Neural Plasticity Markers in Breast Cancer Patients Receiving Chemotherapy: Randomized, Double-Blinded, Placebo-Controlled Trial

Background: Adjuvant chemotherapy for breast cancer (ACBC) has been associated with fatigue, pain, depressive symptoms, and disturbed sleep. And, previous studies in non-cancer patients showed that melatonin could improve the descending pain modulatory system (DPMS). We tested the hypothesis that me...

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Main Authors: Ana Claudia Souza Palmer (Author), Andressa Souza (Author), Vinicius Souza dos Santos (Author), José Antônio Crespo Cavalheiro (Author), Fernando Schuh (Author), Angela Erguy Zucatto (Author), Jorge Villanova Biazus (Author), Iraci Lucena Da S. Torres (Author), Felipe Fregni (Author), Wolnei Caumo (Author)
Format: Book
Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
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