Preparation of nobiletin in self-microemulsifying systems and its intestinal permeability in rats

ABSTRACT: PURPOSE. The objective of this study was to prepare nobiletin self-microemulsifying drug delivery systems (SMEDDS) and investigate its intestinal transport behavior using the single-pass intestinal perfusion (SPIP) method in rat. METHODS. The characterizations of nobiletin SMEDDS were inve...

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Главные авторы: Jing Yao (Автор), Yun Lu (Автор), Jian Ping Zhou (Автор)
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Опубликовано: Frontiers Media S.A., 2008-07-01T00:00:00Z.
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