Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

• Main Authors: Mayo Araki (Author), Massanori Kurihara (Author), Suzuko Kinoshita (Author), Rie Awane (Author), Tetsuya Sato (Author), Yasuyuki Ohkawa (Author), Yoshihiro H. Inoue (Author)
• Format: Book
• Published: The Company of Biologists, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The innate immune response is the first line of defence against microbial infections. In Drosophila, two major pathways of the innate immune system (the Toll- and Imd-mediated pathways) induce the synthesis of antimicrobial peptides (AMPs) within the fat body. Recently, it has been reported that cer...