Assessment of causal effects of physical activity on neurodegenerative diseases: A Mendelian randomization study

• Main Authors: Peng-Fei Wu (Author), Hui Lu (Author), Xiaoting Zhou (Author), Xuchen Liang (Author), Ruizhuo Li (Author), Wan Zhang (Author), Danyang Li (Author), Kun Xia (Author)
• Format: Book
• Published: Elsevier, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Physical activity has been hypothesized to play a protective role in neurodegenerative diseases. However, effect estimates previously derived from observational studies were prone to confounding or reverse causation. Methods: We performed a two-sample Mendelian randomization (MR) analysi...