An In-Silico, In-Vitro and In-Vivo Combined Approach to Identify NMNATs as Potential Protein Targets of ProEGCG for Treatment of Endometriosis

• Main Authors: Sze Wan Hung (Author), Bo Liang (Author), Yating Gao (Author), Ruizhe Zhang (Author), Zhouyurong Tan (Author), Tao Zhang (Author), Pui Wah Jacqueline Chung (Author), Tak Hang Chan (Author), Chi Chiu Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endometriosis is defined as endometrial tissues found outside the uterine cavity. ProEGCG is a prodrug of Epigallocatechin gallate (EGCG), a potent polyphenol found in green tea. It inhibits the development of endometriotic lesions of mouse model in vivo, with higher efficacy and more remarkable ant...