DEPTOR loss impairs brown adipocyte development in vitro but has limited impacts in mice

• Hlavní autoři: Charles Colas (Autor), Mathilde Mouchiroud (Autor), Manal Al Dow (Autor), Alona Kolnohuz (Autor), Yves Gélinas (Autor), Alexandre Caron (Autor), Mathieu Laplante (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2023-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Objectives: The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase that regulates growth and metabolism. In mice, activation of mTOR controls cold adaptation by promoting the recruitment and the activation of brown adipose tissue (BAT). DEP-domain containing mTOR-interacting protein...