Tumor growth inhibition modeling in patients with second line biliary tract cancer and first line non‐small cell lung cancer based on bintrafusp alfa trials

• Main Authors: Ana‐Marija Milenković‐Grišić (Author), Nadia Terranova (Author), Diane R. Mould (Author), Yulia Vugmeyster (Author), Thomas Mrowiec (Author), Andreas Machl (Author), Pascal Girard (Author), Karthik Venkatakrishnan (Author), Akash Khandelwal (Author)
• Format: Book
• Published: Wiley, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This analysis aimed to quantify tumor dynamics in patients receiving either bintrafusp alfa (BA) or pembrolizumab, by population pharmacokinetic (PK)‐pharmacodynamic modeling, and investigate clinical and molecular covariates describing the variability in tumor dynamics by pharmacometric an...