Transferrin receptor targeting segment T7 containing peptide gene delivery vectors for efficient transfection of brain tumor cells

• Main Authors: Ziyao Kang (Author), Chunlan Zeng (Author), Long Tian (Author), Taoran Wang (Author), Sen Yang (Author), Qin Cheng (Author), Jing Zhang (Author), Qingbin Meng (Author), Changhao Zhang (Author), Zhao Meng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Successful gene therapy for brain tumors are often limited by two important factors, the existence of blood brain barrier (BBB) and inefficient transfection of brain tumor cells. In this study, we designed a series of peptide-based gene delivery vectors decorated with T7 segment for binding the tran...