BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice

• Hoofdauteurs: Cuiying Xiao (Auteur), Naili Liu (Auteur), Haley Province (Auteur), Ramón A. Piñol (Auteur), Oksana Gavrilova (Auteur), Marc L. Reitman (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2020-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Bombesin-like receptor 3 (BRS3) is an orphan receptor and Brs3 knockout mice develop obesity with increased food intake and reduced resting metabolic rate and body temperature. The neuronal populations contributing to these effects were examined. Methods: We studied energy metabolism in m...