BRS3 in both MC4R- and SIM1-expressing neurons regulates energy homeostasis in mice

• Main Authors: Cuiying Xiao (Author), Naili Liu (Author), Haley Province (Author), Ramón A. Piñol (Author), Oksana Gavrilova (Author), Marc L. Reitman (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Bombesin-like receptor 3 (BRS3) is an orphan receptor and Brs3 knockout mice develop obesity with increased food intake and reduced resting metabolic rate and body temperature. The neuronal populations contributing to these effects were examined. Methods: We studied energy metabolism in m...