Docosahexaenoic acid and eicosapentaenoic acid strongly inhibit prostanoid TP receptor‐dependent contractions of guinea pig gastric fundus smooth muscle

• Main Authors: Keyue Xu (Author), Miyuki Shimizu (Author), Chika Murai (Author), Miki Fujisawa (Author), Daichi Ito (Author), Noboru Saitoh (Author), Yutaka Nakagome (Author), Mio Yamashita (Author), Azusa Murata (Author), Shunya Oikawa (Author), Guanghan Ou (Author), Kento Yoshioka (Author), Keisuke Obara (Author), Yoshio Tanaka (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The inhibitory effects of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and linoleic acid (LA) on the contractions induced by five prostanoids and U46619 (a TP receptor agonist) were examined in guinea pig gastric fundus smooth muscle (GFSM). Tension changes were isometrically me...