Effect of ASP2205 fumarate, a novel 5-HT2C receptor agonist, on urethral closure function in rats
The pharmacological profile of ASP2205 fumarate (ASP2205), a novel 5-HT2C receptor agonist, was evaluated in vitro and in vivo. ASP2205 showed potent and selective agonistic activity for the human 5-HT2C receptor, with an EC50 of 0.85 nM in the intracellular Ca2+ mobilization assay. Rat 5-HT2C recep...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2019-04-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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