Delayed Administration of Nintedanib Ameliorates Fibrosis Progression in CG-Induced Peritoneal Fibrosis Mouse Model

• Main Authors: Binbin Cui (Author), Chao Yu (Author), Shenglei Zhang (Author), Xiying Hou (Author), Yi Wang (Author), Jun Wang (Author), Shougang Zhuang (Author), Feng Liu (Author)
• Format: Book
• Published: Karger Publishers, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: A multiple-target tyrosine kinase inhibitor, nintedanib, which is approved for treatment of interstitial pulmonary disease, has been demonstrated to have anti-fibrotic activity outside of the lungs. We explored its therapeutic effect in a murine model of peritoneal fibrosis. Methods: Dai...